The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2010
Filed:
Nov. 26, 2002
Hideyuki Okano, Tokyo, JP;
Yoshiaki Toyama, Tokyo, JP;
Masaya Nakamura, Tokyo, JP;
Tatsuji Nomura, Tokyo, JP;
Yoshikuni Tanioka, Kanagawa, JP;
Kiyoshi Ando, Tokyo, JP;
Yonehiro Kanemura, Osaka, JP;
Hideyuki Okano, Tokyo, JP;
Yoshiaki Toyama, Tokyo, JP;
Masaya Nakamura, Tokyo, JP;
Tatsuji Nomura, Tokyo, JP;
Yoshikuni Tanioka, Kanagawa, JP;
Kiyoshi Ando, Tokyo, JP;
Yonehiro Kanemura, Osaka, JP;
Japan Science and Technology Agency, Kawaguchi-shi, JP;
Keio University, Tokyo, JP;
Abstract
A method for creating a monkey model of spinal cord injury, which includes exposing the dura mater of the cervical cord of a monkey and applying a load on the dura mater; the thus-created monkey model of spinal cord injury; and a method for evaluating a therapeutic drug for spinal cord injury by use of this model. According to the present invention, it is possible to create a monkey which is close to the human and thus useful as a model of human spinal cord injury. This model enables proper evaluation of therapeutic effects of various drugs on spinal cord injury. Through use of this model, it has been confirmed for the first time that transplantation therapy of human neural stem cells is efficacious against spinal cord injury.