The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2010

Filed:

Apr. 05, 2005
Applicants:

Mark T. Bilodeau, Lansdale, PA (US);

Chixu Chen, San Diego, CA (US);

Nicholas D. P. Cosford, San Diego, CA (US);

Brian W. Eastman, San Diego, CA (US);

John C. Hartnett, Conshohocken, PA (US);

Essa H. HU, San Diego, CA (US);

Peter J. Manley, Harleysville, PA (US);

Lou Anne Neilson, Sellersville, PA (US);

Lida R. Tehrani, San Diego, CA (US);

Zhicai Wu, Quakertown, PA (US);

Inventors:

Mark T. Bilodeau, Lansdale, PA (US);

Chixu Chen, San Diego, CA (US);

Nicholas D. P. Cosford, San Diego, CA (US);

Brian W. Eastman, San Diego, CA (US);

John C. Hartnett, Conshohocken, PA (US);

Essa H. Hu, San Diego, CA (US);

Peter J. Manley, Harleysville, PA (US);

Lou Anne Neilson, Sellersville, PA (US);

Lida R. Tehrani, San Diego, CA (US);

Zhicai Wu, Quakertown, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 413/12 (2006.01); C07D 521/00 (2006.01); C07D 401/14 (2006.01); C07D 487/08 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.


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