The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2010
Filed:
Aug. 15, 2006
Theodorus S. M. Koopman, Weesp, NL;
Hendrink J. Koster, Weesp, NL;
Peter H. Van Amsterdam, Weesp, NL;
Roelof W. Feenstra, Weesp, NL;
Marinus Verhage, Weesp, NL;
Andrew C. Mccreary, Weesp, NL;
Mayke B. Hesselink, Weesp, NL;
Gustaaf J. M. Van Scharrenburg, Weesp, NL;
Theodorus S. M. Koopman, Weesp, NL;
Hendrink J. Koster, Weesp, NL;
Peter H. Van Amsterdam, Weesp, NL;
Roelof W. Feenstra, Weesp, NL;
Marinus Verhage, Weesp, NL;
Andrew C. McCreary, Weesp, NL;
Mayke B. Hesselink, Weesp, NL;
Gustaaf J. M. Van Scharrenburg, Weesp, NL;
Solvay Pharmaceuticals, B.V., Weesp, NL;
Abstract
The present disclosure relates to N-oxides of certain piperazine and piperidine derivatives and to methods for the preparation of these compounds. The disclosure also relates to the use of the compounds for the manufacture of a medicament giving a beneficial effect. The disclosure also relates to the use of the compounds for the manufacture of a medicament for treating a disease or condition. The disclosure further relates to the treatment of CNS-disorders, in particular the treatment of anxiety disorders, including generalized anxiety disorder and panic disorder, obsessive compulsive disorder, aggression, addiction (including craving), depression, autism, vertigo, schizophrenia and other psychotic disorders, Parkinson's disease and disturbances of cognition and memory. The compounds have the general formula (1) wherein the symbols have the meanings given in the specification.