The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 06, 2010
Filed:
Feb. 22, 2005
Applicants:
Iwan Beuvink, Biel-Benken, CH;
Anne Boulay, Blotzheim, FR;
Heidi Lane, Biel-Benken, CH;
Terence O'reilly, Basel, CH;
George Thomas, Wyoming, OH (US);
Inventors:
Iwan Beuvink, Biel-Benken, CH;
Anne Boulay, Blotzheim, FR;
Heidi Lane, Biel-Benken, CH;
Terence O'Reilly, Basel, CH;
George Thomas, Wyoming, OH (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided are biomarkers for determining the sensitivity of proliferative diseases such as cancer to therapeutic agents, in particular mTOR inhibitors in combination with a cytotoxic agent, in particular a cytotoxic agent which damages or affects the integrity of DNA.