The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2010

Filed:

Dec. 21, 2004
Applicants:

Hidenori Mikamiyama, Osaka, JP;

Minamo Iwata, Osaka, JP;

Yoshiyuki Taoda, Osaka, JP;

Inventors:

Hidenori Mikamiyama, Osaka, JP;

Minamo Iwata, Osaka, JP;

Yoshiyuki Taoda, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 239/02 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula (1), pharmaceuticals containing the same, especially anti-HIV agents having anti viral activity, especially inhibitory activity against HIV integrase, wherein X represents either one of the following groups: (wherein, C ring is nitrogen-containing aromatic heterocyclic ring in which at least one atom in atoms neighboring the atom bound to the pyrimidine ring is unsubstituted nitrogen atom; Ris hydrogen or lower alkyl; D ring is aryl or heteroaryl) Zand Zeach is independently a single bond, O, S, S(═O) or SO; Zis a single bond, lower alkylene or lower alkenylene; Ar is optionally substituted aryl or optionally substituted heteroaryl; Ris lower alkyl, substituted lower alkyl or the like; Ris a hydrogen atom or optionally substituted lower alkyl; or Rand Rmay form, together with an adjacent atom, an optionally substituted heterocyclic ring, a pharmaceutically acceptable salt or a solvate thereof.


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