The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2010

Filed:

Apr. 12, 2005
Applicants:

Hyae Gyeong Cheon, Daejeon, KR;

Sung-eun Yoo, Kongju-si, KR;

Sung Soo Kim, Daejeon, KR;

Sung-don Yang, Daejeon, KR;

Kwang-rok Kim, Daejeon, KR;

Sang Dal Rhee, Daejeon, KR;

Jin Hee Ahn, Daejeon, KR;

Seung Kyu Kang, Daejeon, KR;

Won Hoon Jung, Daejeon, KR;

Sung Dae Park, Seoul, KR;

Nam Gee Kim, Seoul, KR;

Sun Mee Kim, Suwon-si, KR;

Kil Woong MO, Seoul, KR;

Jae Mok Lee, Seoul, KR;

Hye Jung Kang, Suwon-si, KR;

Koun Ho Lee, Seoul, KR;

Jong Hoon Kim, Anyang-si, KR;

Jeong-hyung Lee, Daejeon, KR;

Seung Jun Kim, Daejeon, KR;

Inventors:

Hyae Gyeong Cheon, Daejeon, KR;

Sung-Eun Yoo, Kongju-si, KR;

Sung Soo Kim, Daejeon, KR;

Sung-Don Yang, Daejeon, KR;

Kwang-Rok Kim, Daejeon, KR;

Sang Dal Rhee, Daejeon, KR;

Jin Hee Ahn, Daejeon, KR;

Seung Kyu Kang, Daejeon, KR;

Won Hoon Jung, Daejeon, KR;

Sung Dae Park, Seoul, KR;

Nam Gee Kim, Seoul, KR;

Sun Mee Kim, Suwon-si, KR;

Kil Woong Mo, Seoul, KR;

Jae Mok Lee, Seoul, KR;

Hye Jung Kang, Suwon-si, KR;

Koun Ho Lee, Seoul, KR;

Jong Hoon Kim, Anyang-si, KR;

Jeong-Hyung Lee, Daejeon, KR;

Seung Jun Kim, Daejeon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/216 (2006.01); A61K 31/4402 (2006.01); A61K 31/5375 (2006.01); C07C 69/753 (2006.01); C07D 211/70 (2006.01); C07D 265/32 (2006.01);
U.S. Cl.
CPC ...
Abstract

The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.


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