The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2010

Filed:

Jun. 09, 2005
Applicants:

Pingda Ren, San Diego, CA (US);

Xia Wang, San Diego, CA (US);

Guobao Zhang, San Diego, CA (US);

Qiang Ding, San Diego, CA (US);

Shuli You, Shanghai, CN;

Qiong Zhang, San Diego, CA (US);

Greg Chopiuk, San Diego, CA (US);

Pamela A. Albaugh, Carlsbad, CA (US);

Taebo Sim, San Diego, CA (US);

Nathanael Schiander Gray, Boston, MA (US);

Inventors:

Pingda Ren, San Diego, CA (US);

Xia Wang, San Diego, CA (US);

Guobao Zhang, San Diego, CA (US);

Qiang Ding, San Diego, CA (US);

Shuli You, Shanghai, CN;

Qiong Zhang, San Diego, CA (US);

Greg Chopiuk, San Diego, CA (US);

Pamela A. Albaugh, Carlsbad, CA (US);

Taebo Sim, San Diego, CA (US);

Nathanael Schiander Gray, Boston, MA (US);

Assignee:

IRM LLC, Hamilton, BM;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 31/4178 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, ΣΓK, Tιε2, Λχκ, θNK2α2, MKK4, c-RAF, MKK6, SAPK2α and SAPK2β kinases.


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