The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 2010

Filed:

Oct. 20, 2005
Applicants:

Guenter Hoelzemann, Seeheim-Jugenheim, DE;

Karl-august Ackermann, Ober-Ramstadt, DE;

Helene Crassier, Darmstadt, DE;

Alfred Jonczyk, Darmstadt, DE;

Wilfried Rautenberg, Reinheim, DE;

Gema Tarrason, Barcelona, ES;

Elisabet Rosell-vives, Barcelona, ES;

Jaume Adan, Mataro, ES;

Claudia Cases, Barcelona, ES;

Inventors:

Guenter Hoelzemann, Seeheim-Jugenheim, DE;

Karl-August Ackermann, Ober-Ramstadt, DE;

Helene Crassier, Darmstadt, DE;

Alfred Jonczyk, Darmstadt, DE;

Wilfried Rautenberg, Reinheim, DE;

Gema Tarrason, Barcelona, ES;

Elisabet Rosell-Vives, Barcelona, ES;

Jaume Adan, Mataro, ES;

Claudia Cases, Barcelona, ES;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01); A01N 43/58 (2006.01); A01N 43/60 (2006.01); C07D 413/00 (2006.01); C07D 471/00 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of the formula (I), in which R, R, R, R, Het, X and X' have the meanings indicated in claim, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.


Find Patent Forward Citations

Loading…