The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2010
Filed:
Jul. 18, 2005
Tamara Maes, Barcelona, ES;
Carlos Buesa Arjol, Barcelona, ES;
Marta Barrachina Castillo, Barcelona, ES;
Isidro Ferrer Abizanda, Barcelona, ES;
Tamara Maes, Barcelona, ES;
Carlos Buesa Arjol, Barcelona, ES;
Marta Barrachina Castillo, Barcelona, ES;
Isidro Ferrer Abizanda, Barcelona, ES;
Oryzon Genomics, S.A., Barcelona, ES;
Abstract
The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.