The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2010
Filed:
Oct. 18, 2006
David H. Gelfand, Oakland, CA (US);
Keith A. Bauer, San Rafael, CA (US);
Amar P. Gupta, Danville, CA (US);
Veeraiah Bodepudi, San Ramon, CA (US);
John Niemiec, San Leandro, CA (US);
David H. Gelfand, Oakland, CA (US);
Keith A. Bauer, San Rafael, CA (US);
Amar P. Gupta, Danville, CA (US);
Veeraiah Bodepudi, San Ramon, CA (US);
John Niemiec, San Leandro, CA (US);
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Abstract
The present invention provides reaction mixtures that include blocked oligonucleotides comprising 2'-terminator nucleotides. The blocked oligonucleotides are rendered extendible when the 2′-terminator nucleotides are removed from the oligonucleotides, e.g., via pyrophosphorolysis. The reaction mixtures can be used in various nucleic acid polymerization and/or amplification assays, among many other applications. In addition to reaction mixtures, the invention also provides related methods and reaction mixtures.