The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2010
Filed:
Dec. 12, 2005
Wen-tyng LI, Taipei, TW;
Rung-jiun Gau, Kaohsiung, TW;
Yu-shih Weng, Pingtung, TW;
Cheng-ta Hsieh, Tainan, TW;
Pei-shan LI, Taipei, TW;
Wen-Tyng Li, Taipei, TW;
Rung-Jiun Gau, Kaohsiung, TW;
Yu-Shih Weng, Pingtung, TW;
Cheng-Ta Hsieh, Tainan, TW;
Pei-Shan Li, Taipei, TW;
Industrial Technology Research Institute, Hsinchu, TW;
Abstract
The present invention provides a cell-culturing model and a method for screening compounds which can be applied in treating or preventing hepatic cirrhosis. The cell culturing model comprises a population of hepatocytes and hepatic stellate cells (HSCs) derived from co-culturing, and at least one population of the cells comprises a nucleotide sequence fragment of a reporter gene and a cell specific regulatory sequence. The cell-culturing model of the present invention can be applied in high throughput screening for effective compounds of medication, and also in understanding the functional mechanism of the effective compounds.