The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2010
Filed:
Feb. 02, 2004
Sylvia M. Evans, Del Mar, CA (US);
Ju Chen, San Diego, CA (US);
Chenleng Cai, San Diego, CA (US);
Alessandra Moretti, La Jolla, CA (US);
Kenneth R. Chien, La Jolla, CA (US);
Karl-ludwig Laugwitz, La Jolla, CA (US);
Sylvia M. Evans, Del Mar, CA (US);
Ju Chen, San Diego, CA (US);
Chenleng Cai, San Diego, CA (US);
Alessandra Moretti, La Jolla, CA (US);
Kenneth R. Chien, La Jolla, CA (US);
Karl-Ludwig Laugwitz, La Jolla, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The present invention provides in vitro methods of expansion and propagation of undifferentiated progenitor cells and more specifically undifferentiated progenitor cells containing Islet1, a marker apparently unique to proliferating cardiac stem cells. Methods are described for isolation of stem cell populations as well as for provoking expansion and propagation of undifferentiated progenitor cells without differentiation, to provide cardiac repair or improve cardiac function, for example.