The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 2010
Filed:
Mar. 23, 2007
Youcef M. Rustum, Amherst, NY (US);
Arup Bhattacharya, Amherst, NY (US);
Karoly Toth, N. Amherst, NY (US);
Harry K. Slocum, Buffalo, NY (US);
Rami G. Azrak, Getzville, NY (US);
Sreenivasulu Chintala, Amherst, NY (US);
Mukund Seshadri, Buffalo, NY (US);
Richard Mazurchuk, Clarence, NY (US);
Youcef M. Rustum, Amherst, NY (US);
Arup Bhattacharya, Amherst, NY (US);
Karoly Toth, N. Amherst, NY (US);
Harry K. Slocum, Buffalo, NY (US);
Rami G. Azrak, Getzville, NY (US);
Sreenivasulu Chintala, Amherst, NY (US);
Mukund Seshadri, Buffalo, NY (US);
Richard Mazurchuk, Clarence, NY (US);
Health Research, Inc., Buffalo, NY (US);
Abstract
This invention provides a method for a method for optimizing the regimen for the administration of chemotherapeutic agents. The method comprises administration of a selenium compound to an individual, monitoring the modulation of tumor vessel maturation (TVM) to identify an optimal time for administration of a chemotherapeutic agent. This invention also provides a method to determine whether or not a tumor is likely to be a responder to chemotherapy. The method comprises administration of a selenium compound to an individual and determining whether or not an increase in TVM is observed. An increased TVM following administration of selenium is an indication that the tumor will likely respond the chemotherapy.