The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2010

Filed:

Jul. 12, 2006
Applicants:

Gilbert Gorr, Freiburg, DE;

Heike Launhardt, Freiburg, DE;

Marta Rodriguez Franco, Freiburg, DE;

Christian Stemmer, Freiburg, DE;

Inventors:

Gilbert Gorr, Freiburg, DE;

Heike Launhardt, Freiburg, DE;

Marta Rodriguez Franco, Freiburg, DE;

Christian Stemmer, Freiburg, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01H 5/00 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method for producing heterologous glycosylated proteins in non-animal eukaryotic cells such as in transformed bryophyte, yeast, ciliate or algae cells. In particular, the method relates to a method for producing glycosylated proteins comprising animal glycosylation patterns—comprising sialic acid residues—, such as pharmaceutical proteins for use in mammals, e.g. humans, in bryophyte cells such as those of, the genetic material required therefore, such as DNA and RNA, vectors, host cells, methods of introducing genetic material there into, and uses thereof. Furthermore, the present invention relates to novel polypeptides and proteins obtained by the method according to the invention. Moreover, the present invention provides a method of producing sialic acid or CMP-sialic acid in a transformed non-mammalian eukaryotic cell, tissue or organism.


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