The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2010

Filed:

Feb. 23, 2006
Applicants:

Joan Huguet Clotet, Sant Joan Despi, ES;

Pere Dalmases Barjoan, San Feliu De Llobregat, ES;

Inventors:

Joan Huguet Clotet, Sant Joan Despi, ES;

Pere Dalmases Barjoan, San Feliu De Llobregat, ES;

Assignee:

Inke, S.A., Castellbisal, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 257/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

It is provided a method for obtaining Irbesartan polymorph A, with few synthesis steps, by coupling the intermediate of formula (II) with the compound of formula (III), neutralising one of its alkaline salts in an aqueous medium and recrystallising the crude product obtained. The utilisation of said method obviates protection and deprotection of the tetrazole ring and is therefore of considerable interest for obtaining Irbesartan on a large industrial scale. The invention also refers to the synthesis intermediate of formula (II).


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