The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2010

Filed:

Dec. 07, 2005
Applicants:

Enrique Luis Michelotti, Fort Washington, PA (US);

Eric Bruce Springman, East Norriton, PA (US);

Duyan Nguyen, North Wales, PA (US);

Rupa S. Shetty, King of Prussia, PA (US);

Younghee Lee, Blue Bell, PA (US);

Kristofer Kent Moffett, Blue Bell, PA (US);

Jennifer Lee Ludington, Lansdale, PA (US);

Ted Tsutomis Fujimoto, Churchville, PA (US);

Zenon D. Konteatis, Chatham Twp, NJ (US);

Bin Liu, Dayton, NJ (US);

Frank Hollinger, Blue Bell, PA (US);

Bruce D. Dorsey, Ambler, PA (US);

Inventors:

Enrique Luis Michelotti, Fort Washington, PA (US);

Eric Bruce Springman, East Norriton, PA (US);

Duyan Nguyen, North Wales, PA (US);

Rupa S. Shetty, King of Prussia, PA (US);

Younghee Lee, Blue Bell, PA (US);

Kristofer Kent Moffett, Blue Bell, PA (US);

Jennifer Lee Ludington, Lansdale, PA (US);

Ted Tsutomis Fujimoto, Churchville, PA (US);

Zenon D. Konteatis, Chatham Twp, NJ (US);

Bin Liu, Dayton, NJ (US);

Frank Hollinger, Blue Bell, PA (US);

Bruce D. Dorsey, Ambler, PA (US);

Assignee:

Locus Pharmaceuticals, Inc., Blue Bell, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 273/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to a compound having the formula wherein R, R, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases such as MAP kinases, in particular p38 kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease. The present invention is also directed to a method of treating or preventing a protein kinase-mediated condition.


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