The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2010
Filed:
Jul. 02, 1993
Zelig Eshhar, 76346 Rehovot, IL;
Daniel Schindler, Rehovot, IL;
Tova Waks, 49372 Petach Tikva, IL;
Gideon Gross, D.N. Hevel Korazim, IL;
Zelig Eshhar, 76346 Rehovot, IL;
Daniel Schindler, Rehovot, IL;
Tova Waks, 49372 Petach Tikva, IL;
Gideon Gross, D.N. Hevel Korazim, IL;
Other;
Abstract
Chimeric receptor genes suitable for endowing lymphocytes with antibody-type specificity include a first gene segment encoding a single-chain Fv domain of a specific antibody and a second gene segment encoding all or part of the transmembrane and cytoplasmic domains, and optionally the extracellular domain, of an immune cell-triggering molecule. The chimeric receptor gene, when transfected to immune cells, expresses the antibody-recognition site and the immune cell-triggering moiety into one continuous chain. The transformed lymphocytes are useful in therapeutic treatment methods.