The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2010
Filed:
May. 19, 2004
Marc Nazare, Idstein, DE;
Michael Wagner, Alsbach, DE;
Volkmar Wehner, Sandberg, DE;
Hans Matter, Langenselbold, DE;
Matthias Urmann, Eschborn, DE;
Kurt Ritter, Frankfurt am Main, DE;
Marc Nazare, Idstein, DE;
Michael Wagner, Alsbach, DE;
Volkmar Wehner, Sandberg, DE;
Hans Matter, Langenselbold, DE;
Matthias Urmann, Eschborn, DE;
Kurt Ritter, Frankfurt am Main, DE;
sanofi-aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention relates to compounds of the formula I, wherein R, R, R, Q, V, G and M are as defined herein. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.