The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2010
Filed:
Sep. 06, 2007
Eckhard Guenther, Maintal, DE;
Olaf Schaefer, Biberach an der Riss, DE;
Michael Teifel, Weiterstadt, DE;
Klaus Paulini, Maintal, DE;
Eckhard Guenther, Maintal, DE;
Olaf Schaefer, Biberach an der Riss, DE;
Michael Teifel, Weiterstadt, DE;
Klaus Paulini, Maintal, DE;
Aeterna Zentaris GmbH, Frankfurt, DE;
Abstract
The present invention provides conjugates of disorazoles and their derivatives with cell-binding molecules, such as peptides, proteins, hormones, blood proteins and antibodies. The present invention further provides novel disorazole derivatives and processes of manufacturing such conjugates and disorazole derivatives. These compounds can be used as medicaments for the treatment of physiological and/or pathophysiological conditions in mammals, in particular for the treatment of various tumors.