The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2010

Filed:

May. 31, 2006
Applicants:

S. Ananth Karumanchi, Chestnut Hill, MA (US);

Vikas P. Sukhatme, Newton, MA (US);

Mourad Toporsian, Toronto, CA;

Michelle V. Letarte, Toronto, CA;

Inventors:

S. Ananth Karumanchi, Chestnut Hill, MA (US);

Vikas P. Sukhatme, Newton, MA (US);

Mourad Toporsian, Toronto, CA;

Michelle V. Letarte, Toronto, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using combinations of compounds that alter soluble endoglin and sFlt-1 expression levels or biological activity. Also disclosed are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using compounds that increase endothelial nitric oxide synthase levels or biological activity.


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