The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2010

Filed:

Jul. 18, 2005
Applicants:

Barrett Allan, Encinitas, CA (US);

Weidong Jiang, Sunnyvale, CA (US);

Ying Tang, San Diego, CA (US);

Jeffry Dean Watkins, Encinitas, CA (US);

Inventors:

Barrett Allan, Encinitas, CA (US);

Weidong Jiang, Sunnyvale, CA (US);

Ying Tang, San Diego, CA (US);

Jeffry Dean Watkins, Encinitas, CA (US);

Assignee:

Applied Molecular Evolution, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12N 15/13 (2006.01); C12N 15/63 (2006.01); C12N 15/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides humanized anti-CD20 antibodies comprising a human IgG1 Fc region comprising an isoleucine at position 247 and a glutamine at position 339 as well as nucleic acids encoding the antibodies and methods of using the antibodies for treating lymphoma. Furthermore, the invention provides compositions comprising the antibodies and methods of producing them.


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