The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2010

Filed:

Oct. 17, 2007
Applicants:

Jogeshwar Mukherjee, Irvine, CA (US);

Elizabeth Head, Irvine, CA (US);

Crystal Wang, La Palma, CA (US);

Pooja C. Patel, Stockton, CA (US);

Inventors:

Jogeshwar Mukherjee, Irvine, CA (US);

Elizabeth Head, Irvine, CA (US);

Crystal Wang, La Palma, CA (US);

Pooja C. Patel, Stockton, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/13 (2006.01); C07C 255/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods are contemplated in which senile plaques and/or neurofibrillary tangles are labeled using compounds with improved permeability across the blood brain barrier and improved selective binding to senile plaques and/or neurofibrillary tangles. Contemplated compounds are derivatives of FDDNP or curcumin, which most preferably have improved solubility in aqueous solvents. Labeling is typically performed using a PET detectable label, and especiallyC andF.


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