The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2010

Filed:

Aug. 16, 2006
Applicants:

Katsuhiro Kawakami, Tokyo, JP;

Kazuo Kanai, Tokyo, JP;

Takao Horiuchi, Tokyo, JP;

Hiroshi Takeshita, Tokyo, JP;

Syozo Kobayashi, Tokyo, JP;

Yuichi Sugimoto, Tokyo, JP;

Issei Achiwa, Tokyo, JP;

Junichi Kuroyanagi, Tokyo, JP;

Inventors:

Katsuhiro Kawakami, Tokyo, JP;

Kazuo Kanai, Tokyo, JP;

Takao Horiuchi, Tokyo, JP;

Hiroshi Takeshita, Tokyo, JP;

Syozo Kobayashi, Tokyo, JP;

Yuichi Sugimoto, Tokyo, JP;

Issei Achiwa, Tokyo, JP;

Junichi Kuroyanagi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 413/14 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 413/12 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 263/56 (2006.01); C07D 263/58 (2006.01); A61K 31/496 (2006.01); A61K 31/4439 (2006.01); A61K 31/427 (2006.01); A61K 31/428 (2006.01); A61K 31/423 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
Abstract

A 1,6-β-glucan synthetase inhibitor is provided, having potent growth inhibition and having excellent safety. A compound is provided, capable of expressing in a wide spectral range and specifically or selectively, an antifungal effect based on its functional mechanism of 1,6-β-glucan synthesis inhibition. Also provided is a drug, a salt or hydrate thereof, especially an antifungal that contains the compound. Concretely, provided is a compound of the following formula (I), its salt or hydrate, and a drug or antifungal containing, as the active ingredient, the compound, its salt or hydrate:


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