The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2010
Filed:
Dec. 07, 2005
Applicants:
Evan R. Lewis, Pacifica, CA (US);
Mark Nguyen Ho, San Jose, CA (US);
Fabiana N. Fonseca, New York, NY (US);
Inventors:
Evan R. Lewis, Pacifica, CA (US);
Mark Nguyen Ho, San Jose, CA (US);
Fabiana N. Fonseca, New York, NY (US);
Assignee:
Onyx Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); C08B 37/16 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed.