The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2010
Filed:
Apr. 18, 2005
Noriaki Shirahama, Bungoono, JP;
Tomokazu Mukai, Bungoono, JP;
Takao Okada, Kakogawa, JP;
Yukari Imamura, Himeji, JP;
Yoshimichi Fujiyama, Kakogawa, JP;
Noriaki Shirahama, Bungoono, JP;
Tomokazu Mukai, Bungoono, JP;
Takao Okada, Kakogawa, JP;
Yukari Imamura, Himeji, JP;
Yoshimichi Fujiyama, Kakogawa, JP;
Kawasumi Laboratories, Inc., Tokyo, JP;
Abstract
Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/ε-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater,2<()<[%/(%+%+%)]××0.058  (1)1<()<[%/(%+%+%)]××0.58  (2)1<()<[%/(%+%+%)]××0.58  (3) wherein L(LA), L(GA) and L(CL) represent average chain lengths of lactic acid units, glycolic acid units and of caprolactone units, LA%, GA% and CL% represent molar ratios of a lactic acid component, a glycolic acid component caprolactone component in the copolymer and X is a polymerization degree of the copolymer.