The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Sep. 26, 2005
Mikkel Boas Thygesen, Copenhagen East, DK;
Nathalie Schlienger, Frederiksberg, DK;
Bo-ragnar Tolf, Malmö, SE;
Carl-magnus A. Andersson, Hjärup, SE;
Fritz Blatter, Reinach, CH;
Jörg Berghausen, Lörrach, DE;
Mikkel Boas Thygesen, Copenhagen East, DK;
Nathalie Schlienger, Frederiksberg, DK;
Bo-Ragnar Tolf, Malmö, SE;
Carl-Magnus A. Andersson, Hjärup, SE;
Fritz Blatter, Reinach, CH;
Jörg Berghausen, Lörrach, DE;
ACADIA Pharmaceuticals Inc., San Diego, CA (US);
Abstract
Disclosed herein are methods for synthesizing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)-phenylmethyl)carbamide. Also disclosed herein is the hemi-tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2 -methylpropyloxy)-phenylmethyl)carbamide and methods for obtaining the salt. Further disclosed are various crystalline forms of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)-phenylmethyl)carbamide and its hemi-tartrate salt including various polymorphs and solvates.