The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Jun. 05, 2008
Graeme Cameron Murray Smith, Cambridge, GB;
Niall Morrison Barr Martin, Cambridge, GB;
Keith Allan Menear, Cambridge, GB;
Marc Geoffrey Hummersone, Cambridge, GB;
Laurent Jean Martin Rigoreau, London, GB;
Roger John Griffin, Newcastle upon Tyne, GB;
Bernard Thomas Golding, Newcastle upon Tyne, GB;
David Richard Newell, Newcastle upon Tyne, GB;
Hilary Alan Calvert, Newcastle upon Tyne, GB;
Nicola Jane Curtin, Newcastle upon Tyne, GB;
Ian Robert Hardcastle, Newcastle upon Tyne, GB;
Kappusamy Saravanan, Newcastle upon Tyne, GB;
Graeme Cameron Murray Smith, Cambridge, GB;
Niall Morrison Barr Martin, Cambridge, GB;
Keith Allan Menear, Cambridge, GB;
Marc Geoffrey Hummersone, Cambridge, GB;
Laurent Jean Martin Rigoreau, London, GB;
Roger John Griffin, Newcastle upon Tyne, GB;
Bernard Thomas Golding, Newcastle upon Tyne, GB;
David Richard Newell, Newcastle upon Tyne, GB;
Hilary Alan Calvert, Newcastle upon Tyne, GB;
Nicola Jane Curtin, Newcastle upon Tyne, GB;
Ian Robert Hardcastle, Newcastle upon Tyne, GB;
Kappusamy Saravanan, Newcastle upon Tyne, GB;
Kudos Pharmaceuticals Limited, Cambridge, GB;
Cancer Research Technology Limited, London, GB;
Abstract
A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: Rand Rare independently selected from hydrogen, an optionally substituted Calkyl group, Cheterocyclyl group, or Caryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; Q is —NH—C(═O)— or —O—; Y is an optionally substituted Calkylene group; X is selected from SRor NRR, wherein, R, or Rand Rare independently selected from hydrogen, optionally substituted Calkyl, Caryl, or Cheterocyclyl groups, or Rand Rmay together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; if Q is —O—, X is additionally selected from —C(═O)—NRR, wherein Rand Rare independently selected from hydrogen, optionally substituted Calkyl, Caryl, or Cheterocyclyl groups, or Rand Rmay together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; and if Q is —NH—C(═O)—, —Y—X may additionally be selected from Calkyl.