The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2010

Filed:

Jun. 05, 2007
Applicants:

Weidong Zhang, Shanghai, CN;

Hanxiong LI, Guangzhou, CN;

Huiliang LI, Shanghai, CN;

Chuan Zhang, Shanghai, CN;

Runhui Liu, Shanghai, CN;

Juan Su, Shanghai, CN;

Xike Xu, Shanghai, CN;

Inventors:

Weidong Zhang, Shanghai, CN;

Hanxiong Li, Guangzhou, CN;

Huiliang Li, Shanghai, CN;

Chuan Zhang, Shanghai, CN;

Runhui Liu, Shanghai, CN;

Juan Su, Shanghai, CN;

Xike Xu, Shanghai, CN;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4738 (2006.01); C07D 491/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for preparing dehydrocavidine, dehydroapocavidine and their respective composition is provided. The composition is first prepared by isolating and purifying the quaternary ammonium alkaloid components from the medicinal plant 'Yan Huang Lian' (Bunting) through the processes of solvent extraction, water-phase organic extraction, crystallization and recrystallization, and then drying to obtain said composition containing dehydrocavidine and dehydroapocavine. When necessary, the composition or their crude extracts can be separated by chromatography to obtain dehydrocavidine or dehydroapocavidine. Dehydrocavidine, dehydroapocavidine or their respective composition can be used in manufacturing medicines for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia.


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