The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Sep. 03, 2004
Hiromu Habashita, Mishima-gun, JP;
Hiroshi Ochiai, Mishima-gun, JP;
Natsuko Tokuda, Mishima-gun, JP;
Shiro Shibayama, Tsukuba, JP;
Noriki Watanabe, Tsukuba, JP;
Takaki Komiya, Tsukuba, JP;
Kazuhiko Takeda, Tsukuba, JP;
Hiromu Habashita, Mishima-gun, JP;
Hiroshi Ochiai, Mishima-gun, JP;
Natsuko Tokuda, Mishima-gun, JP;
Shiro Shibayama, Tsukuba, JP;
Noriki Watanabe, Tsukuba, JP;
Takaki Komiya, Tsukuba, JP;
Kazuhiko Takeda, Tsukuba, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
The present invention relates to a compound represented by formula (I), a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof, and medical use thereof (the symbols in the formula are as described in the specification). The compound represented by formula (I) has chemokine receptor (especially in CCR4 and/or CCR5) antagonistic activity. Therefore it is useful for prevention and/or treatment of a chemokine receptor-mediated disease such as inflammatory and/or allergic diseases [systemic inflammatory response syndrome (SIRS), anaphylaxis, anaphylactoid reaction, allergic angiitis, transplant rejection reaction, hepatitis, nephritis, nephropathy, pancreatitis, rhinitis, arthritis, inflammatory ocular disease, inflammatory bowel disease, disease in cerebro and/or circulatory system, respiratory disease, dermatosis, autoimmune disease, and the like], infection [viral disease (human immunodeficiency virus infection, acquired immunodeficiency syndrome, SARS, etc.), and the like], and the like.