The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Jul. 24, 2006
Michael Bernd, Frankfurt, DE;
Bernhard Kutscher, Maintal, DE;
Eckhard Gunther, Maintal, DE;
Peter Romeis, Gelnhausen, DE;
Thomas Reissmann, Frankfurt, DE;
Thomas Beckers, Constance, DE;
Michael Bernd, Frankfurt, DE;
Bernhard Kutscher, Maintal, DE;
Eckhard Gunther, Maintal, DE;
Peter Romeis, Gelnhausen, DE;
Thomas Reissmann, Frankfurt, DE;
Thomas Beckers, Constance, DE;
Zentaris GmbH, , DE;
Abstract
The invention relates to peptides which contain N-methylated amino acid units and have improved water solubility. The invention also relates methods for treating a hormone-dependent tumor or a non-malignant indication that is treatable by LH-RH suppression, the method comprising administering to a patient in need of the treatment a therapeutically effective amount of a compound of the invention. Hormone-dependent cancers that can be treated with the methods of the invention include prostate cancer, breast cancer, ovarian cancer, endometrial cancer, and pancreatic cancer. Non-malignant indications which can be treated by the methods of the invention include benign prostate hyperplasia (BPH), endometriosis, acne, polycystic ovarian disease, dysmenorrhea, precocious puberty, and uterine fibroids and other leiomyomas.