The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Sep. 10, 2007
Christopher J. Woolverton, Kent, OH (US);
Gary D. Niehaus, Kent, OH (US);
Kathleen J. Doane, Ravenna, OH (US);
Oleg D. Lavrentovich, Kent, OH (US);
Steven P. Schmidt, Akron, OH (US);
Steven A. Signs, Hudson, OH (US);
Christopher J. Woolverton, Kent, OH (US);
Gary D. Niehaus, Kent, OH (US);
Kathleen J. Doane, Ravenna, OH (US);
Oleg D. Lavrentovich, Kent, OH (US);
Steven P. Schmidt, Akron, OH (US);
Steven A. Signs, Hudson, OH (US);
Kent State University, Kent, OH (US);
Abstract
A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an enzyme, whereby the enzyme is separated from its substrate by an receptor; and a receptor engineered to inhibit the active of site of an enzyme only in the absence of a ligand. Also provided are methods for the automatic detection of ligands.