The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2010

Filed:

Aug. 14, 2003
Applicants:

Hae-young Suh, Suwon-si, KR;

Sung-soo Kim, Seoul, KR;

Ji-won Kim, Suwon-si, KR;

Young-don Lee, Suwon-si, KR;

Seung-cheol Ahn, Seoul, KR;

Inventors:

Hae-Young Suh, Suwon-si, KR;

Sung-Soo Kim, Seoul, KR;

Ji-Won Kim, Suwon-si, KR;

Young-Don Lee, Suwon-si, KR;

Seung-Cheol Ahn, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/00 (2006.01); C12N 5/08 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This inventive discloses a method for transdifferentiating mesenchymal stem cells into neuronal cells, which comprises increasing the level of a basic helix-loop-helix (bHLH) transcription factor in the mesenchymal stem cells, said cells being useful in cell therapy or gene therapy for treating brain neurological diseases such as Parkinson's disease, Alzheimer disease, Hungtington's disease, amyotrophic lateral sclerosis, cerebral paralysis and brain ischemia; and spine disfunction caused by a traumatic injury.


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