The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Mar. 14, 2007
Torsten Hoffman, Halle/Saale, DE;
Stephan Schilling, Halle/Saale, DE;
Andre J. Niestroj, Sennewitz, DE;
Hans-ulrich Demuth, Haale/Saale, DE;
Ulrich Heiser, Halle/Saale, DE;
Mirko Buchholz, Halle/Saale, DE;
Torsten Hoffman, Halle/Saale, DE;
Stephan Schilling, Halle/Saale, DE;
Andre J. Niestroj, Sennewitz, DE;
Hans-Ulrich Demuth, Haale/Saale, DE;
Ulrich Heiser, Halle/Saale, DE;
Mirko Buchholz, Halle/Saale, DE;
Probiodrug AG, Halle (Salle), DE;
Abstract
The present invention provides novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC, methods for screening for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity. Preferred compositions additionally comprise inhibitors of DP IV or DP IV-like enzymes for the treatment or alleviation of conditions that can be treated by modulation of QC- and DP IV-activity.