The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 2010

Filed:

Sep. 06, 2004
Applicants:

Yukio Nagasaki, Moriya, JP;

Kazunori Kataoka, Tokyo, JP;

Takehiko Ishii, Washimiya-machi, JP;

Tadahito Takahashi, Yokohama, JP;

Inventors:

Yukio Nagasaki, Moriya, JP;

Kazunori Kataoka, Tokyo, JP;

Takehiko Ishii, Washimiya-machi, JP;

Tadahito Takahashi, Yokohama, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/553 (2006.01); G01N 33/544 (2006.01); G01N 33/547 (2006.01); G01N 33/537 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a method to detect analyte which comprises preparing fine particles which have a chargeable group in their core and a hydrophilic polymer chain in their shell; obtaining an agglutinated matter by forming a biologically specific bond between a specific residue on the surface of fine particles and analyte, and by simultaneously forming a bond by the electrostatic interaction between impure protein and said particles; and subsequently cleaving only the latter bond by raising ionic intensity. Thus, this invention provides a method to detect analyte with rapidity and high sensitivity with use of agglutination reaction.


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