The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2010
Filed:
Mar. 29, 2004
Applicants:
Jay A. Berzofsky, Bethesda, MD (US);
Takahiro Okazaki, Yokohama, JP;
Inventors:
Jay A. Berzofsky, Bethesda, MD (US);
Takahiro Okazaki, Yokohama, JP;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides peptides and proteins for use in second generation HIV vaccines and as diagnostic tools in the treatment and control of HIV infection. The antiviral protection shown by compositions of the present invention has not been previously achieved with an HLA epitope-enhanced vaccine. These findings define a critical balance between MHC affinity and receptor crossreactivity required for effective epitope enhancement and also demonstrate construction and efficacy of such a component of a new generation vaccine.