The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2010
Filed:
Apr. 13, 2006
Applicants:
Arto Karjalainen, Espoo, FI;
Seppo Parhi, Oulu, FI;
Inventors:
Arto Karjalainen, Espoo, FI;
Seppo Parhi, Oulu, FI;
Assignee:
Orion Corporation, Espoo, FI;
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/58 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method of isolating detomidine (I) hydrochloride as a crystalline salt is provided. The method comprises hydrogenating in the presence of a catalyst of compound of formula (II) in aqueous solution comprising hydrochloric acid, concentrating the solution by distillation, optionally adding hydrochloric acid to the concentrated solution, cooling the concentrated solution and recovering the crystallized detomidine hydrochloride. The product can be recovered directly from aqueous solution with