The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2010

Filed:

Aug. 07, 2008
Applicants:

Jean-yves Reginster, Angleur, BE;

Michelle Deberg, Embourg, BE;

Yves Henrotin, Beaufays, BE;

Stephan Christgau, Gantofte, DK;

Inventors:

Jean-Yves Reginster, Angleur, BE;

Michelle Deberg, Embourg, BE;

Yves Henrotin, Beaufays, BE;

Stephan Christgau, Gantofte, DK;

Assignee:

Universite de Liege, Liege, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.


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