The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2010

Filed:

Dec. 28, 2004
Applicants:

Katsumasa Nonoshita, Ibaraki, JP;

Makoto Ishikawa, Ibaraki, JP;

Hiroshi Nakashima, Ibaraki, JP;

Daisuke Tsukahara, Ibaraki, JP;

Yoshio Ogino, Ibaraki, JP;

Fumiko Sakai, Ibaraki, JP;

Yoshikazu Nagae, Ibaraki, JP;

Keisuke Arakawa, Ibaraki, JP;

Teruyuki Nishimura, Ibaraki, JP;

Inventors:

Katsumasa Nonoshita, Ibaraki, JP;

Makoto Ishikawa, Ibaraki, JP;

Hiroshi Nakashima, Ibaraki, JP;

Daisuke Tsukahara, Ibaraki, JP;

Yoshio Ogino, Ibaraki, JP;

Fumiko Sakai, Ibaraki, JP;

Yoshikazu Nagae, Ibaraki, JP;

Keisuke Arakawa, Ibaraki, JP;

Teruyuki Nishimura, Ibaraki, JP;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

A glucokinase activator is provided; and a remedy and/or a preventive for diabetes, or a remedy and/or a preventive for diabetes such as retinopathy, nephropathy, neurosis, ischemic cardiopathy, arteriosclerosis, and further a remedy and/or a preventive for obesity are provided. A glucokinase activator characterized by containing a 2-heteroaryl-substituted benzimidazole derivative of a general formula (I-0) or its pharmaceutically-acceptable salt: [in the formula, X represents a carbon atom or a nitrogen atom; (in the formula, X represents a carbon atom or a nitrogen atom); Rrepresents an aryl, etc.; Rrepresents a hydroxy, etc.; Rrepresents a —Calkyl, etc.; Rrepresents a —Calkyl, etc.; Xrepresents —O—, etc.; a indicates an integer of 1, 2 or 3; q indicates an integer of from 0 to 2; m indicates an integer of from 0 to 2].


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