The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 2010
Filed:
Apr. 18, 2005
Pere Dalmases Barjoan, Sant Feliu de Llobregat, ES;
Jordi Bessa Belmunt, Barcelona, ES;
Joan Huguet Clotet, Sant Joan Despi, ES;
Juan Antonio Perez Andres, Sant Joan Despi, ES;
Pere Dalmases Barjoan, Sant Feliu de Llobregat, ES;
Jordi Bessa Belmunt, Barcelona, ES;
Joan Huguet Clotet, Sant Joan Despi, ES;
Juan Antonio Perez Andres, Sant Joan Despi, ES;
INKE, S.A., Castellbisbal, ES;
Abstract
This invention relates to a process for preparing intermediates useful in preparing Valsartan and to a process for preparing the latter, together with synthesis intermediates of formula (IV), (V) and (VI), useful for manufacturing a medicament for the treatment of arterial hypertension or heart failure. The process for preparing Valsartan permits it to be prepared on an industrial scale with high yields and without racemisation problems, in addition to using simple and available starting products. The invention also provides a process for preparing the intermediate of formula (VI), from an intermediate of formula (V) that does not require protection of the carboxylic acid prior to N-acylation.