The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 2010

Filed:

Dec. 11, 2006
Applicants:

Varghese John, San Francisco, CA (US);

Michel Maillard, Redwood Shores, CA (US);

Barbara Jagodzinska, Redwood City, CA (US);

James Beck, Kalamazoo, MI (US);

Andrea Gailunas, Burlingame, CA (US);

John Freskos, Clayton, MO (US);

John Mickelson, Dexter, MI (US);

Lakshman Samala, Plainsboro, NJ (US);

Jennifer Sealey, Burlingame, CA (US);

Ruth Tenbrink, Labadie, MO (US);

Larry Fang, Foster City, CA (US);

Roy Hom, San Francisco, CA (US);

Inventors:

Varghese John, San Francisco, CA (US);

Michel Maillard, Redwood Shores, CA (US);

Barbara Jagodzinska, Redwood City, CA (US);

James Beck, Kalamazoo, MI (US);

Andrea Gailunas, Burlingame, CA (US);

John Freskos, Clayton, MO (US);

John Mickelson, Dexter, MI (US);

Lakshman Samala, Plainsboro, NJ (US);

Jennifer Sealey, Burlingame, CA (US);

Ruth Tenbrink, Labadie, MO (US);

Larry Fang, Foster City, CA (US);

Roy Hom, San Francisco, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., So. San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/133 (2006.01); C07D 217/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds of the formula wherein the variables R, R, R, R, R, and Rare as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of disorders such as Alzheimer's Disease.


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