The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7727750 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 01, 2010

Filed:

Apr. 03, 2008
Applicants:

Steven Paul Hanlon, Bottmingen, CH;

Hans Iding, Rheinfelden, DE;

Ernst Kupfer, Zurich, CH;

Roumen Nikolaev Radinov, West Caldwell, NJ (US);

Lianhe Shu, Livingston, NJ (US);

Ping Wang, Nutley, NJ (US);

Inventors:

Steven Paul Hanlon, Bottmingen, CH;

Hans Iding, Rheinfelden, DE;

Ernst Kupfer, Zurich, CH;

Roumen Nikolaev Radinov, West Caldwell, NJ (US);

Lianhe Shu, Livingston, NJ (US);

Ping Wang, Nutley, NJ (US);

Assignee:

Hoffman-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 17/12 (2006.01); C12P 1/04 (2006.01); C07D 241/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to biocatalytic asymmetric reduction for the preparation of 2-amino-[5-(1-hydroxy-2-hydroxy or halogen-ethyl)]-pyrazine derivatives of the formula wherein R is lower alkylcarbonyl or an amino protecting group and Ris hydroxy or halogen. The compounds are key intermediates in the manufacture of a glucokinase activator.


Find Patent Forward Citations

Hanlon, Steven. (2010). Biocatalytic asymmetric reduction in preparation of (s)-n-[5-(1,2-dihydroxy-ethyl)-pyrazinyl]-2,2-dimethyl-propionamide (U.S. Patent No. 7727750). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7727750

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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