The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7727731 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 01, 2010

Filed:

Jun. 28, 2002
Applicants:

Alain Moussy, Paris, FR;

Patrice Dubreuil, Marseilles, FR;

Olivier Hermine, Palaiseau, FR;

Inventors:

Alain Moussy, Paris, FR;

Patrice Dubreuil, Marseilles, FR;

Olivier Hermine, Palaiseau, FR;

Assignee:

AB Science, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12Q 1/18 (2006.01); C12Q 1/48 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a screening method allowing the identification and selection of compounds targeting the transphosphorylase (also called phosphotransferase) domain of c-kit, more particularly compounds selected to be potent inhibitors of constitutively activated c-kit, while being unable to inhibit other activation pathways as for example the pathways leading to death of IL-3 dependent cells cultured in presence of IL-3.


Find Patent Forward Citations

Moussy, Alain. (2010). Potent, selective and non toxic c-kit inhibitors (U.S. Patent No. 7727731). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7727731

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