The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Nov. 08, 2007
Peter Herold, Allschwil, CH;
Robert Mah, Allschwil, CH;
Stefan Stutz, Allschwil, CH;
Aleksandar Stojanovic, Allschwil, CH;
Isabelle Lyothier, Allschwil, CH;
Dirk Behnke, Allschwil, CH;
Peter Herold, Allschwil, CH;
Robert Mah, Allschwil, CH;
Stefan Stutz, Allschwil, CH;
Aleksandar Stojanovic, Allschwil, CH;
Isabelle Lyothier, Allschwil, CH;
Dirk Behnke, Allschwil, CH;
Novartis AG, Basel, CH;
Abstract
Process for preparing a compound of the formula (I) in which Rand Rare each independently H, C-C-alkyl, halogen, polyhalo-C-C-alkoxy, polyhalo-C-C-alkyl, C-C-alkoxy, C-C-alkoxy-C-C-alkyl, or C-C-alkoxy-C-C-alkoxy, where Rand Rare not both H, and Ris C-C-alkyl, which is characterized in that a) a compound of the formula (II) in which Rand Rare each as defined above and X is Br, I, triflate, toyslate or mesylate is reacted with prop-2-yn-1-ol to give the compound of the formula (III), b) the compound of the formula (III) is reacted with an alkyl-metal compound in which 'alkyl' is as defined above for Rto give a compound of the formula (I).