The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Feb. 18, 2000
Andreas Bergmann, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils Gernot Morgenthaler, Berlin, DE;
Alan P. Johnstone, Surrey, GB;
Philip S. Shepherd, Surrey, GB;
Andreas Bergmann, Berlin, DE;
Joachim Struck, Berlin, DE;
Nils Gernot Morgenthaler, Berlin, DE;
Alan P. Johnstone, Surrey, GB;
Philip S. Shepherd, Surrey, GB;
B.R.A.H.M.S. Aktiengesellschaft, Hennigsdorf, DE;
Abstract
Use of blocking antibodies against the human TSH receptor (hTSH receptor) or their specifically binding fragments for the treatment of, or for preparation of drugs for the treatment of, hyperthyroidism which is attributable to stimulating autoantibodies against the hTSH receptor (Graves' disease) or overstimulation of the thyroid gland by endogenous TSH or to activating mutations of the hTSH receptor, and for the treatment of Graves' ophthalmopathy, and specific blocking monoclonal antibodies which recognize the minimum sequence FDSH corresponding to the positions 381 to 384 of the human TSH receptor.