The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2010

Filed:

Feb. 08, 2006
Applicants:

Steven R. Ledbetter, Westborough, MA (US);

Celia P. Hart, Noyarey, FR;

Robert G. Holgate, Granta Park, GB;

Lutz U. Jermutus, Granta Park, GB;

Catriona L. Buchanan, Granta Park, GB;

Alexander R. Duncan, Granta Park, GB;

Donna K. Finch, Granta Park, GB;

Inventors:

Steven R. Ledbetter, Westborough, MA (US);

Celia P. Hart, Noyarey, FR;

Robert G. Holgate, Granta Park, GB;

Lutz U. Jermutus, Granta Park, GB;

Catriona L. Buchanan, Granta Park, GB;

Alexander R. Duncan, Granta Park, GB;

Donna K. Finch, Granta Park, GB;

Assignees:

Optein, Inc., Wilmington, DE (US);

Genzyme Corporation, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); C07K 14/495 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGFβ), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralize TGFβ1, TGFβ2 and TGFβ3, so-called 'pan-specific' antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).


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