The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Jan. 30, 2007
Adnan M. M. Mjalli, Oak Ridge, NC (US);
Dharma R. Polisetti, High Point, NC (US);
Govindan Subramanian, Bellemeade, NJ (US);
James C. Quada, High Point, NC (US);
Ravindra R. Yarragunta, Greensboro, NC (US);
Robert C. Andrews, Jamestown, NC (US);
Rongyuan Xie, Greensboro, NC (US);
Adnan M. M. Mjalli, Oak Ridge, NC (US);
Dharma R. Polisetti, High Point, NC (US);
Govindan Subramanian, Bellemeade, NJ (US);
James C. Quada, High Point, NC (US);
Ravindra R. Yarragunta, Greensboro, NC (US);
Robert C. Andrews, Jamestown, NC (US);
Rongyuan Xie, Greensboro, NC (US);
TransTech Pharma, Inc., High Point, NC (US);
Abstract
The present invention provides imidazole derivatives of Formula (I-IV), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I-IV), and their use in treating human or animal disorders. The compounds of the invention inhibit protein tyrosine phosphatase 1B and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes.