The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2010

Filed:

Mar. 21, 2007
Applicants:

Wayne Vaccaro, Yardley, PA (US);

Zhong Chen, Princeton, NJ (US);

Dharmpal S. Dodd, Princeton, NJ (US);

Tram N. Huynh, Pennington, NJ (US);

James Lin, Lawrenceville, NJ (US);

Chunjian Liu, Pennington, NJ (US);

Christopher P. Mussari, Princeton, NJ (US);

John S. Tokarski, Princeton, NJ (US);

David R. Tortolani, Skillman, NJ (US);

Stephen T. Wrobleski, Whitehouse Station, NJ (US);

Shuqun Lin, Newtown, PA (US);

Inventors:

Wayne Vaccaro, Yardley, PA (US);

Zhong Chen, Princeton, NJ (US);

Dharmpal S. Dodd, Princeton, NJ (US);

Tram N. Huynh, Pennington, NJ (US);

James Lin, Lawrenceville, NJ (US);

Chunjian Liu, Pennington, NJ (US);

Christopher P. Mussari, Princeton, NJ (US);

John S. Tokarski, Princeton, NJ (US);

David R. Tortolani, Skillman, NJ (US);

Stephen T. Wrobleski, Whitehouse Station, NJ (US);

Shuqun Lin, Newtown, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/5025 (2006.01); A61P 19/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are useful as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR, and R, R, R, X and Y are as defined herein.


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