The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 25, 2010

Filed:

Feb. 23, 2004
Applicants:

Reinhold Penner, Honolulu, HI (US);

Andrea Flieg, Honolulu, HI (US);

Inventors:

Reinhold Penner, Honolulu, HI (US);

Andrea Flieg, Honolulu, HI (US);

Assignee:

The Queens's Medical Center, Honolulu, HI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to methods useful in identifying molecules that bind TRPM5, which modulate TRPM5 ion channel activity, and/or which alter expression of TRPM5 within cells. The TRPM5 channels as described herein contain TRPM5 polypeptides, which are in turn encoded by TRPM5 nucleic acids. The ion channels described herein are preferably formed in HEK-293 cells from one or more novel TRPM5 polypeptides, which exhibit one or more of the unique TRPM5 properties described herein.


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