The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Jan. 16, 2008
Applicants:
Michael Karpusas, Upper Darby, PA (US);
Paul D. Lyne, Arlington, MA (US);
Jose William Saldanha, Enfield, GB;
Ellen A. Garber, Cambridge, MA (US);
Inventors:
Michael Karpusas, Upper Darby, PA (US);
Paul D. Lyne, Arlington, MA (US);
Jose William Saldanha, Enfield, GB;
Ellen A. Garber, Cambridge, MA (US);
Assignee:
Biogen Idec MA Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/87 (2006.01); C12N 5/20 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.