The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Dec. 19, 2003
Ana Velasco Iglesias, Madrid, ES;
Fernando DE LA Calle, Madrid, ES;
Tomás Aparicio Pérez, Madrid, ES;
Carmen Schleissner Sánchez, Madrid, ES;
Paloma Acebo Páis, Madrid, ES;
Pilar Rodríguez Ramos, Madrid, ES;
Fernando Reyes Benítez, Madrid, ES;
Rubén Henrìquez Peláez, Madrid, ES;
Ana Velasco Iglesias, Madrid, ES;
Fernando de la Calle, Madrid, ES;
Tomás Aparicio Pérez, Madrid, ES;
Carmen Schleissner Sánchez, Madrid, ES;
Paloma Acebo Páis, Madrid, ES;
Pilar Rodríguez Ramos, Madrid, ES;
Fernando Reyes Benítez, Madrid, ES;
Rubén Henrìquez Peláez, Madrid, ES;
PharmaMar, S.A., Madrid, ES;
Abstract
A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ ID NO:1, variants or portions thereof, or at least one of the sacA, sacB, sacC, sacC, sacD, sacE, sacF, sacG, sacH, sacH, saI, sacJ, orf1, orf2, orf3 or orf4 genes, including variants or portions.